The first macrolide discovered was erythromycin, which was first used in 1952. Erythromycin was widely used as a substitute to penicillin in cases where patients were allergic to penicillin or …

Feb 18, 2025 · Your healthcare provider may prescribe a macrolide antibiotic if it’s the best medication to treat your specific type of infection. Macrolides are also an alternative if you’re …

Because macrolides are active against atypical respiratory pathogens, they are often used empirically for lower respiratory tract infections, but another antibiotic is often necessary to …

Dec 28, 2025 · Erythromycin was the first macrolide discovered (isolated from Streptomyces erythreus in the 1950s), followed by newer “second-generation” and “third-generation” agents …

Therefore, macrolides are often referred to as “tunnel plugs”. Macrolide antibiotics are known to have antiviral effects. Macrolide antibiotics can be taken orally or given as an intravenous …

Erythromycin was the first macrolide discovered; other macrolides include azithromycin, clarithromycin, and roxithromycin. Their action is primarily bacteriostatic but may be …

Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. Thus, macrolides have been viewed as …

Therefore, pregnant women should not take With the macrolide clarithromycin, harmful effects on the fetus have been observed in animal studies. Therefore, pregnant women should not …

Jul 20, 2025 · Macrolide antibiotics are a class of drugs derived from bacteria, distinguished by their large macrocyclic lactone ring structure. These medications treat a wide variety of …

Dec 22, 2025 · Macrolide, class of antibiotics characterized by their large lactone ring structures and by their growth-inhibiting (bacteriostatic) effects on bacteria. The macrolides were first …