MECP2 appears to be essential for the normal function of nerve cells. The protein seems to be particularly important for mature nerve cells, where it is present in high levels. The MECP2 …

What is MECP2 duplication syndrome? MECP2 duplication syndrome is a rare neurodevelopmental condition caused by an extra copy (duplication) of the MECP2 gene. The …

Jan 18, 2008 · Both loss of MECP2 (see Genetically Related Disorders) and duplication of MECP2 lead to intellectual disability syndrome, indicating that a correct dose of the protein is …

In the brain, the MeCP2 protein is important for the function of several types of cells, including nerve cells (neurons). The protein likely plays a role in maintaining connections (synapses) …

Nov 14, 2025 · MECP2 (Methyl-CpG Binding Protein 2) is a Protein Coding gene. Diseases associated with MECP2 include Rett Syndrome and Encephalopathy, Neonatal Severe, Due …

Aug 1, 2025 · The MECP2 gene encodes methyl-CpG binding protein 2 (MeCP2), which plays an important role in neuronal development through epigenetic regulation of gene expression.

Aug 2, 2025 · Understanding this gene provides insight into normal human biology and the origins of certain complex neurological conditions. This article explores the MECP2 gene, its …

Mutations in methyl CpG binding protein 2 (MeCP2) are the major cause of Rett syndrome (RTT), a rare neurodevelopmental disorder with a notable period of developmental regression …

Proteins that recognize and bind to methylated bases in DNA include the methylated DNA-binding protein MECP2.

MECP2 duplication syndrome (M2DS) is a rare disease that is characterized by severe intellectual disability and impaired motor function. It is an X-linked genetic disorder caused by the …