MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression. Front. Immunol. 14:1102282.1-1102282.10 …

The cell line MC38 is a commonly used murine model for colorectal carcinoma. It has a high mutational burden, is sensitive to immune checkpoint immunotherapy and endogenous CD8+ T cell responses …

MC-38 Cell Line derived from C57BL6 murine colon adenocarcinoma cells. From the laboratories of James W. Hodge, PhD, MBA and Jeffrey Schlom, PhD, National Cancer Institute/NIH. This product …

Mar 1, 2019 · The MC38 murine colon carcinoma model can be employed as a robust preclinical immuno-oncology model. Our data supports the use of this tool in investigating novel treatment …

Aug 4, 2025 · The MC38 cell line is a widely recognized preclinical model in cancer research, particularly for studying colorectal cancer. These cells provide a consistent platform for scientists to investigate …

MC38 is an established and well-characterized cellular model for colorectal cancer, exhibiting a rapid growth rate and expressing the colon epithelium markers claudin-1 and SATB.

Mar 1, 2019 · The MC38 murine colon carcinoma model can be employed as a robust preclinical immuno-oncology model. Our data supports the use of this tool in investigating novel treatment …

geneic C57BL6 murine hosts or immunocompromised mice. The MC38 colon adenocarcinoma model, especially when used in orthotopic mouse models, is recognized for its immunological …

Jul 31, 2025 · The MC38 tumor model is a well-established cell line used in colorectal cancer research. It originated from a mouse colon adenocarcinoma, specifically induced in a C57BL/6 mouse by the …

Mar 8, 2023 · Introduction: The cell line MC38 is a commonly used murine model for colorectal carcinoma. It has a high mutational burden, is sensitive to immune checkpoint immunotherapy and …