Japanese scientists have developed a new method for DNA amplification and sequencing that improves the accuracy of single-cell RNA sequencing (scRNA-seq). The new method called TAS-Seq uses a terminal ...

A fundamental cornerstone of the era of “genetic engineering” was the development of technology that allowed researchers to determine a DNA sequence in its linear order. Given the advent of ...

A new method for DNA amplification and sequencing called TAS-Seq improves the accuracy of single-cell RNA sequencing (scRNA-seq). TAS-Seq uses a terminal transferase enzyme that amplifies and ...

A) DNA polymerase binds to a single-stranded DNA template (blue) and synthesizes a complementary strand of DNA (red). B) When DNA polymerase randomly incorporates a fluorescently labeled ddNTP base, ...