A partnership between St. Jude and Mustang Bio may change the challenges faced by those diagnosed with what is commonly referred to as “bubble boy disease.” A partnership between St. Jude and Mustang ...

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. Patients with ...

X-linked severe combined immunodeficiency disease (X-SCID) is a rare genetic disorder characterized by profound defects in T-cell, B-cell, and natural killer (NK) cell function, caused by mutations in ...

SAN FRANCISCO (KPIX 5) - In the late 1970s, and early 1980s, a small boy with dark eyes was known as "David, the Bubble Boy." In order to survive, the slender dark-haired youngster was forced to live ...

The California Institute for Regenerative Medicine has awarded a five-year, $11.9 million grant to St. Jude Children's Research Hospital and collaborators to deliver gene therapy to patients with ...

The cytokine receptor common gamma chain (γc) is shared among the receptors for interleukin (IL)-2, -4, -7, -9, -15, and plays a pivotal role in transmitting these cytokine signals. 1,2 Many of these ...

Ten children with an especially rare and hard-to-treat form of "bubble boy" disease are living normal lives after receiving a new gene therapy approach, researchers say. Experts said the findings are ...

Several infants treated with autologous ex vivo gene therapy for newly diagnosed X-linked severe combined immunodeficiency (X-SCID) in a phase I/II trial have developed fully functioning immune ...

Federal authorities have temporarily suspended three gene therapy experiments -- two of them in Los Angeles -- following news that a third child in a similar French study has developed leukemia and ...

Researchers used an experimental gene therapy to develop a possible treatment for a rare and deadly immune disorder known as “bubble boy” disease, the National Institutes of Health (NIH) announced ...