“Taken together, these findings reveal a novel role of Runx1 in maintaining disc health and regulating age-related degenerative processes.” “Taken together, these findings reveal a novel role of Runx1 ...

Researchers have identified the role of transcription factors Runx1 and Runx2 in the inhibition of fibrosis, the abnormal build-up of connective tissue with severe hematopoietic defects, in the bone ...

Figure 1: The RUNX1/AP-1 axis operates differently in different types of AML. Cytokine receptors are indicated in different colours with their ligand shown as coloured round shapes on the cell surface ...

The investigators initially believed that targeting RUNX1 was the best approach, but current technologies were limited. mRNA is primarily used to increase protein expression, whereas the issue in PVR ...

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer. Scientists led by the Department of ...