A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

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Small proteins, Vellappan emphasized, are emerging as key subjects of research. Scientists worldwide are seeking a deeper level of understanding about the myriad mechanisms underlying the function of ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

Australian scientists have used Artificial Intelligence (AI) to generate a ready-to-use biological protein that can kill antibiotic resistant bacteria like E. coli. In the last year, there has been a ...

Maintaining a consistent, high-density E. coli culture under consistent growth conditions allows the system to perform ...

Proteins need to fold into specific shapes to perform their functions in cells, but they occasionally misfold, which can prevent them from properly functioning and even lead to disease. A study by ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...