Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Researchers studying the human brain shared a lot of fascinating research this year, like how to keep brains young and how to ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

UNC School of Medicine research reveals a pain control pathway from the cortex to cerebellum crucial for placebo analgesia – when the expectation of pain relief leads to pain alleviation without a ...

For decades, opioids have been the blunt instrument of modern pain care, powerful enough to quiet severe suffering yet risky ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...