The growth of tumors depends in part on its microenvironment, a dynamic area surrounding the tumor, which can include normal cells, supporting structures and molecules. Cancer cells can exert a major ...

Whether they're damaged by injury or disease, or simply conducting the daily maintenance required for life, organisms have to make new cells. That generally requires replicating the organism's genome ...

A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique. Consequently, cells with mutated p53 have a survival advantage, which can cause cancer.

Somatic Mutation PCR Testing Suppresses Amplification of Wild-Type Template DNA, Selectively Amplifies Mutant Templates In the context of personalized cancer treatment, the “gold standard” for tumor ...

Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer The ...

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of events during blood cell production. "We know that many diseases—and all cancers ...