When interferons were first discovered in the 1950s, it was hoped that these naturally occurring chemicals could do for viruses what penicillin did for bacterial infections. Although that wish didn't ...

According to an old medical maxim repeated in the New England Journal of Medicine last week, symptoms of the common cold, “if treated vigorously, will go away within seven days, whereas if left alone ...

In severe cases of COVID-19, a person’s immune system throws everything it has at the coronavirus, but some of the weapons it lobs end up hurting the patient instead of fighting the virus. Now ...

Known as first responders to viral infection, Type I interferons may also play a part—for better or worse—in neurodegenerative disease. At AD/PD 2022, held March 15-20 online and in Barcelona, Spain, ...

Over the past 35 years, interferons have been explored in various formulations for the management of Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), such as essential ...

A new study published on the preprint site medRxiv* in May 2020 reports on the efficacy of interferons in treating COVID-19. The research could help evaluate the place of such therapy in the ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

Researchers have examined five SARS-CoV-2 variants to determine how each strain interacts with the innate arm of the immune system -- the first line of defense in the immune system versus the antibody ...

Saphnelo, a human monoclonal antibody, is a type 1 interferon (INF) receptor antagonist that inhibits a key protein in the immune system called the IFNAR receptor. This protein acts like a transmitter ...

Medically reviewed by Brigid Dwyer, MD Key Takeaways Disease-modifying therapies slow down the progression of multiple ...