Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

High-speed atomic force microscopy (HS-AFM) is the only experimental technique to directly watch proteins in dynamic action. However, as a surface scanning technique with limited spatial resolution, ...

(Nanowerk News) Allowing the direct observation of biomolecules in dynamic action, high-speed AFM has opened a new avenue to dynamic structural biology. An enormous amount of successful applications ...

In this interview, News-Medical Life Science talks to Professor Toshio Ando about his interest in high-speed AFM and how it can revolutionize the observation of protein molecules. How did your ...

The predicted orientation of the Cas9 protein on the AFM substrate is shown, and a simulated AFM image calculated in the scanning view perspective shows remarkable agreement with previous HS-AFM ...

KANAZAWA, Japan, March 19, 2021 /PRNewswire/ -- Researchers at Kanazawa University report in Review of Scientific Instruments a newly developed atomic force microscopy approach for imaging biological ...

New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques. (Nanowerk News) An enzyme type noted in several ...

A collaboration team of researchers from the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, the Institute of Transformative Bio-Molecules (WPI-ITbM), Graduate School of Science at ...

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and ...

An intrinsic limitation in AFM imaging is that only the surface topography can be acquired, and the AFM tip is too large to resolve details below the nanometer scale. To facilitate the interpretation ...