To pack two meters of DNA into a microscopic cell, the string of genetic information must be wound extremely carefully into chromosomes. Surprisingly the DNA's sequence causes it to be coiled and ...

DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability, which can in turn ...

DNA uncoils from the nucleosome asymmetrically (uncoiling from one end much more easily) scientists have discovered. The DNA is packaged into chromosomes, which resemble beaded bracelets. The string ...